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Ibrutinib plus venetoclax is recommended as an option for untreated chronic lymphocytic leukaemia (cll) or small lymphocytic lymphoma (sll) in adults All the criteria as described in the appropriate blueteq form are met and an application for use has been approved. Retreatment with ibrutinib or acalabrutinib was effective for patients who experienced disease relapse. Ibrutinib plus venetoclax achieved higher undetectable mrd rates and extended pfs compared to ibrutinib alone or fcr in cll patients
The combination of ibrutinib and venetoclax has been shown to improve outcomes in patients with chronic lymphocytic leukemia (cll) as compared with chemoimmunotherapy.
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